MEGAN6 Download Page
This is the official download site for the most recent version of MEGAN 6.
The Community Edition of the paper is described here:
Huson et al,, (2016), PLoS Computational Biology
Please post questions and bug reports to the
community website.
MEGAN6 Community Edition installers:
This is
open source.
MEGAN_Community_macos_6_25_9.dmg
MEGAN_Community_unix_6_25_9.sh
MEGAN_Community_unix_ARM_6_25_9.sh
MEGAN_Community_windows-x64_6_25_9.exe
The following file maps NCBI-nr accessions to taxonomic and functional classes (NCBI, GTDB, EC, eggNOG, InterPro2GO, SEED), unzip before use:
megan-map-Feb2022.db.zip
The following file maps genomic DNA accessions to taxonomic classes, unzip before use:
megan-nucl-Feb2022.db.zip
MEGAN6 Ultimate Edition installers (require license key):
MEGAN6 Ultimate Edition is licensed by Computomics GmbH. Apply for a trial license here.
The Ultimate Edition comes with the latest KEGG classification and pathway files.
MEGAN_Ultimate_macos_6_25_9.dmg
MEGAN_Ultimate_unix_6_25_9.sh
MEGAN_Ultimate_unix_ARM_6_25_9.sh
MEGAN_Ultimate_windows-x64_6_25_9.exe
The following mapping file only works with MEGAN Ultimate Edition. It contains KEGG, as well as NCBI, GTDB, eggNOG, InterPro2GO and SEED, unzip before use:
megan-map-Feb2022-ue.db.zip
Mapping file for working with the SILVA SSU (and/or LSU) database:
SSURef_132_Nr99_tax_silva_to_NCBI_synonyms.map.gz
LSURef_132_tax_silva_to_NCBI_synonyms.map.gz
SSURef_NR99_128_tax_silva_to_NCBI_synonyms.map.gz
Provide this file to MEGAN as a synonyms mapping file when importing alignments against the Silva database. No need to decompress before use.
Expanded mapping files:
Very large mapping files to be used with special purpose protein databases:
megan-map-Jul2020-2-X.db.zip
megan-map-Jul2020-2-X-ue.db.zip
Use DIAMOND+MEGAN with AnnoTree:
Download AnnoTree proteins and an associated MEGAN mapping database:
AnnoTree for MEGAN
Additional files:
Release notes
Manual
MeganServer Manual
md5sums.txt
Old files:
Old mapping files and installers