MEGAN-AnnoTree Download Page
This is the download site for files required to use DIAMOND+MEGAN together with the AnnoTree protein reference database.
This approach is described in:
Gautam, Felderhoff, Bagci and Huson, Using AnnoTree to get more assignments, faster, for
DIAMOND+MEGAN microbiome analysis, mSystems Vol. 7 No.1, 22. February 2022.
link.
AnnoTree protein reference sequences:
Create a DIAMOND index for the following file:
annotree.fasta.gz
MEGAN mapping DB:
The following file maps AnnoTree accessions to taxonomic and functional classes (NCBI, GTDB, EC, eggNOG, InterPro2GO, SEED),
unzip before use:
megan-mapping-annotree-June-2021.db.zip
Scripts to create release:
Description of how to create a new release of the above files: AnnoTree_Update_Manual.pdf
Scripts: automatic_annotree_db_update.zip